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That changed after chemist Bruce Merrifield developed solid-phase peptide synthesis, a breakthrough that earned him the Nobel Prize in 1984 and dramatically simplified production of these fragile biomolecules by allowing them to be built much more efficiently compared to purification
10.1124/jpet.112.199497 J
Say NO to neurodegeneration: role of S-nitrosylation in neurodegenerative disorders
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Effect of Semaglutide on Coronary Atherosclerosis Progression in Patients With Type II Diabetes: Rationale and Design of the Semaglutide Treatment on Coronary Progression Trial
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